111 CAH (21-HYDROXYLASE DEFICIENCY) PRESENTING AS CENTRAL PRECOCIOUS PUBERTY

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Congenital adrenal hyperplasia- presenting as central precocious puberty

Results 3 were boys, out of which 2 were twins. 3 boys were diagnosed to have CAH after presentation to the OPD. They had mean bone age of 12 years. They had elevated testosterone (mean : 2.4 ng/ml) and 17 hydoxyprogesterone ( mean : 24 ng/ml ) at presentation. They had clinical (testicular volume 5ml) and biochemical (mean basal LH : 6 ng/ml )evidence of central precocious puberty. The girl wa...

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[Central precocious puberty].

Central precocious puberty, defined as the onset of puberty before the age 8 years in girls and 9 years in boys, results from a premature activation of gonadotropin-releasing hormone neurons in the hypothalamus. This condition is characterised by early pubertal changes, acceleration of growth velocity, and rapid bone maturation that often result in reduced adult height. It may be either idiopat...

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EXPERIENCE WITH 115 PATIENTS WITH CONGENITAL A DREN AL HYPERPLASIA AND EVALUATION OF GROWTH PATTERNS IN 24 PATIENTS WITH THE SALT-LOSING TYPE

In this study the data on 115 cases of congenital adrenal hyperplasia (CAH) who were followed in the Pediatric Endocrine Clinic at Nemazee Hospital, Shiraz will be reported. Among these cases 51 were male and 64 female. The most common type of CAH in these patients was the salt-losing type of 21 -hydroxylase deficiency (85 .2%). ll-hydroxylase deficiency was present in 13.04% of patients. ...

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بررسی 10 ساله تظاهرات بالینی و شیوع انواع هیپرپلازی مادرزادی آدرنال در انستیتو غدد درون‌ریز و متابولیسم

    Background & Objective: Congenital Adrenal Hyperplasia(CAH) includes a group of inherited diseases which are caused by enzyme defects in the synthesis of cortisol from cholesterol. It manifests itself in different forms like ambiguous genitalia, adrenal crisis in infants, precocious puberty in children, hirsutism, oligomenorrhea and infertility in adults. Although CAH is one of the most com...

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Serum vitamin D levels in girls with central precocious puberty

Precocious puberty can cause several adverse effects on final growth and social behavior in girls. Recently studies showed that low serum vitamin D levels might be associated with precocious puberty. The aim of  this research was to investigate the association between serum vitamin D levels and central precocious puberty in girls. Girls with central precocious puberty under the age of 8 we...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1985

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-198506000-00131